Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824858 | 0.84 | MAPT (0.60) | ALDH1A1MAPTRECQLLMNAHPGD | |
| SCHEMBL16261606 | 0.83 | MAPT (0.63) | ALDH1A1MAPTRECQLLMNAHPGD | |
| SCHEMBL10426116 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTADRB1ADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL10426727 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTADRB1ADRB2ADRB3 | |
| SCHEMBL7460280 | 0.80 | JAK2 (0.48) | ALDH1A1MAPTRECQLADRB1ADRB2 | |
| SCHEMBL5851742 | 0.80 | HTR6 (0.64) | ALDH1A1ADRB1LMNAKDM4EHTR6 | |
| SCHEMBL13105531 | 0.79 | MAPT (0.43) | ALDH1A1MAPTRECQLLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL7001932 | 0.79 | HTR6 (0.62) | ALDH1A1ADRB1LMNAKDM4EHTR6 | |
| SCHEMBL10680323 | 0.79 | JAK2 (0.50) | ALDH1A1MAPTRECQLADRB1ADRB2 | |
| SCHEMBL7301452 | 0.78 | JAK2 (0.64) | ALDH1A1MAPTRECQLADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481299-B1 | N-phenyl-piperidyl-4-amines and drugs containing them | BASF AG (DE) | 1994-07-20 | — | — | EP | disclosed |
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| EP-0481299-A2 | N-phenyl-piperidyl-4-amines and drugs containing them | BASF Aktiengesellschaft (DE) | 1992-04-22 | — | — | EP | disclosed |