SCHEMBL7302965

SCHEMBL7302965

CCCc1nc2ccc(-c3cn4cc(C(N)=O)ccc4n3)cc2n1Cc1ccc(-c2ccccc2OC(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 16/20 0.54
AGTR1 P30556 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7302960 0.90 PPARG (0.68) PPARGAGTR1
SCHEMBL7310465 0.89 PPARG (0.56) PPARG
SCHEMBL7301055 0.88 AGTR1 (0.53) PPARGAGTR1
SCHEMBL7302131 0.86 PPARG (0.55) PPARGAGTR1
SCHEMBL7301703 0.84 AGTR1 (0.54) PPARGAGTR1
SCHEMBL7302720 0.84 PPARG (0.54) PPARG
SCHEMBL7302680 0.83 PPARG (0.47) PPARGAGTR1
SCHEMBL9040388 0.83 PPARG (0.60) PPARGAGTR1
SCHEMBL7310738 0.83 PPARG (0.55) PPARG
SCHEMBL7301796 0.83 PPARG (0.56) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502314-A1 Benzimidazol, medicaments containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1992-09-09 EP disclosed