Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.51 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 7/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.49 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855296 | 0.90 | CYP24A1 (0.63) | CYP19A1MTNR1ACYP24A1CYP26A1METAP1 | |
| SCHEMBL7295884 | 0.88 | CYP19A1 (0.65) | CYP19A1MTNR1ACYP24A1CYP26A1METAP1 | |
| SCHEMBL11403440 | 0.83 | MTNR1A (0.68) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8599809 | 0.82 | CYP19A1 (0.62) | CYP19A1MTNR1ACYP24A1CYP26A1METAP1 | |
| SCHEMBL31374633 | 0.81 | ALDH1A1 (0.52) | CYP19A1CYP24A1CYP27A1ACHE | |
| SCHEMBL6644734 | 0.81 | ALDH1A1 (0.52) | CYP19A1CYP24A1CYP27A1ACHE | |
| SCHEMBL11011369 | 0.80 | METAP1 (0.76) | CYP19A1CYP24A1CYP26A1METAP1CYP27A1 | |
| SCHEMBL8434825 | 0.79 | CYP19A1 (0.60) | CYP19A1MTNR1ACYP24A1CYP26A1METAP1 | |
| SCHEMBL14061633 | 0.79 | CYP24A1 (0.60) | CYP19A1CYP24A1CYP26A1METAP1CYP27A1 | |
| Hydrochloric Acid SCHEMBL4623159 | 0.79 | METAP1 (0.78) | CYP19A1CYP24A1CYP26A1METAP1CYP27A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |