Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341542 | 0.78 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL2819403 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2MAOBMETAP1CA1CA2 | |
| SCHEMBL7832178 | 0.78 | SMN1; SMN2 (0.59) | DGAT1SMN1; SMN2MTNR1AMTNR1BMETAP1 | |
| SCHEMBL345330 | 0.76 | SMN1; SMN2 (0.81) | SMN1; SMN2MTNR1AMTNR1BMAOBMETAP1 | |
| SCHEMBL3431949 | 0.76 | POLA1 (0.49) | MTNR1AMTNR1B | |
| SCHEMBL14061713 | 0.76 | SMN1; SMN2 (0.57) | DGAT1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL13254665 | 0.75 | SMN1; SMN2 (0.60) | SMN1; SMN2MTNR1AMTNR1BMAOBMETAP1 | |
| SCHEMBL14409344 | 0.75 | HTR2A (0.53) | SMN1; SMN2MAOBMETAP1CA1CA2 | |
| SCHEMBL11735201 | 0.75 | DRD2 (0.46) | SMN1; SMN2MAOB | |
| SCHEMBL17211804 | 0.75 | DGAT1 (0.60) | DGAT1SMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |