Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742835 | 0.93 | ITGB3 (0.51) | ITGB3ITGA2BPTPN1FOLH1F10 | |
| SCHEMBL7299599 | 0.93 | ITGB3 (0.51) | ITGB3ITGA2BPTPN1FOLH1F10 | |
| Trifluoroacetic Acid SCHEMBL3040708 | 0.89 | ITGB3 (0.50) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL7327332 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1FOLH1F10 | |
| SCHEMBL7438806 | 0.88 | ITGB3 (0.71) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL7321414 | 0.88 | EPHX2 (0.54) | ITGB3ITGA2BPTPN1EPHX2 | |
| SCHEMBL7336239 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BFOLH1F10 | |
| Hydrochloric Acid SCHEMBL9435247 | 0.87 | ITGB3 (0.70) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL9103107 | 0.87 | ITGB3 (0.70) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL9098464 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | claimed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | claimed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | claimed |
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |