Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303040 | 0.87 | ITGB3 (0.55) | ITGB3ITGA2BFOLH1F10 | |
| SCHEMBL7328520 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BFOLH1MAPK1F10 | |
| SCHEMBL7305759 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BFOLH1MAPK1F10 | |
| SCHEMBL7332549 | 0.82 | FOLH1 (0.49) | ITGB3ITGA2BFOLH1PRSS1TMPRSS15 | |
| SCHEMBL7304969 | 0.80 | ITGB3 (0.72) | ITGB3ITGA2BMAPK1 | |
| SCHEMBL7332658 | 0.80 | ITGB3 (0.52) | ITGB3ITGA2BFOLH1PRSS1TMPRSS15 | |
| SCHEMBL9215193 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BFOLH1F10 | |
| SCHEMBL9742835 | 0.79 | ITGB3 (0.51) | ITGB3ITGA2BFOLH1PRSS1TMPRSS15 | |
| SCHEMBL7299599 | 0.79 | ITGB3 (0.51) | ITGB3ITGA2BFOLH1PRSS1TMPRSS15 | |
| Trifluoroacetic Acid SCHEMBL9217427 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2BFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | claimed |