Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 10/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.36 |
| ▸ | PDE2A | O00408 | 5/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315126 | 0.86 | THRB (0.38) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7311762 | 0.85 | PDE3B (0.37) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7321124 | 0.82 | PDE3B (0.43) | MEN1KMT2AGAAALDH1A1PDE3B | |
| SCHEMBL7320170 | 0.81 | KMT2A (0.37) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7312687 | 0.78 | PDE3B (0.47) | MEN1KMT2AGAAALDH1A1PDE3B | |
| SCHEMBL7319480 | 0.77 | PDE3B (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2PDE3B | |
| SCHEMBL7347456 | 0.76 | PDE3B (0.45) | MEN1KMT2AGAAALDH1A1PDE3B | |
| SCHEMBL7316866 | 0.76 | ALDH1A1 (0.39) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7310329 | 0.75 | HPGD (0.44) | MEN1KMT2AGAAALDH1A1PDE3B | |
| SCHEMBL7306819 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |