Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316866 | 0.85 | ALDH1A1 (0.39) | KMT2AGAAMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7306819 | 0.84 | ALDH1A1 (0.38) | KMT2AGAAMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7321124 | 0.82 | PDE3B (0.43) | KMT2AGAAMEN1ALDH1A1HPGD | |
| SCHEMBL7303053 | 0.81 | MEN1 (0.37) | KMT2AGAAMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7312687 | 0.80 | PDE3B (0.47) | KMT2AGAAMEN1ALDH1A1HPGD | |
| SCHEMBL7314747 | 0.79 | SIGMAR1 (0.38) | KMT2AGAAMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7308594 | 0.78 | NPSR1 (0.38) | KMT2AGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7311336 | 0.76 | SIRT3 (0.36) | KMT2AGAAMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10377348 | 0.75 | PDE3B (0.52) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL7317566 | 0.75 | THRB (0.44) | KMT2AALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |