Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ITGAL | P20701 | 4/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303060 | 1.00 | LMNA (0.69) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL4508732 | 0.85 | ALDH1A1 (0.70) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL4508736 | 0.85 | ALDH1A1 (0.70) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL27568108 | 0.85 | RAB9A (0.72) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7302886 | 0.84 | NPC1 (0.63) | MEN1KMT2AALDH1A1CYP1A2RAB9A | |
| SCHEMBL7302887 | 0.84 | NPC1 (0.63) | MEN1KMT2AALDH1A1CYP1A2RAB9A | |
| SCHEMBL11618539 | 0.84 | CYP1A2 (0.66) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11618537 | 0.84 | CYP1A2 (0.66) | LMNAMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL5324731 | 0.83 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2ITGALMAPT | |
| SCHEMBL5324726 | 0.83 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2ITGALMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |