Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908045 | 0.86 | C5AR1 (0.35) | KEAP1KMT2AMMP9NFE2L2PPARG | |
| SCHEMBL28836238 | 0.86 | C5AR1 (0.35) | KEAP1KMT2AMMP9NFE2L2PPARG | |
| SCHEMBL28836284 | 0.85 | LMNA (0.41) | KEAP1MMP9NFE2L2MMP3 | |
| SCHEMBL29908082 | 0.85 | LMNA (0.41) | KEAP1MMP9NFE2L2MMP3 | |
| SCHEMBL28952548 | 0.85 | ADAMTS5 (0.34) | KEAP1KMT2ANFE2L2ALDH1A1TSHR | |
| SCHEMBL29908090 | 0.85 | ADAMTS5 (0.34) | KEAP1KMT2ANFE2L2ALDH1A1TSHR | |
| SCHEMBL7356253 | 0.85 | F2 (0.38) | KEAP1KMT2AMMP13NFE2L2ALDH1A1 | |
| SCHEMBL9729728 | 0.85 | F2 (0.38) | KEAP1KMT2AMMP13NFE2L2ALDH1A1 | |
| SCHEMBL28836306 | 0.81 | MDM2 (0.38) | KEAP1KMT2ANFE2L2 | |
| SCHEMBL29907979 | 0.81 | MDM2 (0.38) | KEAP1KMT2ANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990002137-A1 | RENIN INHIBITORY PEPTIDES CONTAINING SULEPTANIC ACID OR DERIVATIVES THEREOF | THE UPJOHN COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |
| EP-0355065-A1 | Renin inhibitory peptides containing suleptanic acid or derivatives thereof | THE UPJOHN COMPANY (US) | 1990-02-21 | — | — | EP | disclosed |