Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | ESRRG | P62508 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ESRRB | O95718 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9272571 | 0.99 | ST14 (0.58) | ST14ITGB3ITGA2BCA1CA2 | |
| SCHEMBL7303178 | 0.88 | MEN1 (0.52) | ST14CA1CA2CA9ESRRG | |
| Hydrochloric Acid SCHEMBL9254391 | 0.87 | ST14 (0.54) | ST14ITGB3ITGA2BF2F10 | |
| SCHEMBL7296789 | 0.87 | ITGB3 (0.50) | ST14ITGB3ITGA2BF2F10 | |
| Hydrochloric Acid SCHEMBL9275424 | 0.87 | MAPT (0.51) | ST14CA1CA2CA9ESRRG | |
| Hydrochloric Acid SCHEMBL9269810 | 0.86 | ITGB3 (0.49) | ST14ITGB3ITGA2BF2F10 | |
| SCHEMBL7303775 | 0.85 | ST14 (0.54) | ST14ITGB3ITGA2BRAB9AMAPT | |
| SCHEMBL9452125 | 0.85 | ST14 (0.54) | ST14ITGB3ITGA2BRAB9AMAPT | |
| SCHEMBL7297516 | 0.85 | ST14 (0.64) | ST14ITGB3ITGA2BCA1CA2 | |
| Hydrochloric Acid SCHEMBL9269736 | 0.84 | ST14 (0.53) | ST14ITGB3ITGA2BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |