Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SDCBP | O00560 | 1/20 | 0.41 |
| ▸ | SDC2 | P34741 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124249 | 0.85 | NAMPT (0.53) | NAMPTL3MBTL1MAPTTDP1GAA | |
| SCHEMBL3180689 | 0.81 | L3MBTL1 (0.61) | NAMPTL3MBTL1MAPTTDP1GAA | |
| SCHEMBL11090977 | 0.80 | NAMPT (0.53) | NAMPTL3MBTL1MAPTTDP1GAA | |
| SCHEMBL15599335 | 0.80 | NAMPT (0.53) | NAMPTL3MBTL1MAPTTDP1GAA | |
| SCHEMBL25920561 | 0.80 | NAMPT (0.59) | NAMPTL3MBTL1MAPTTDP1CA1 | |
| SCHEMBL13497484 | 0.79 | TDP1 (0.56) | NAMPTL3MBTL1MAPTTDP1GAA | |
| SCHEMBL732456 | 0.79 | NAMPT (0.57) | NAMPTL3MBTL1MAPTTDP1GAA | |
| SCHEMBL1164796 | 0.78 | L3MBTL1 (0.56) | NAMPTL3MBTL1MAPTTDP1GAA | |
| SCHEMBL7768956 | 0.77 | L3MBTL1 (0.52) | NAMPTL3MBTL1MAPTTDP1GAA | |
| SCHEMBL7768959 | 0.77 | L3MBTL1 (0.52) | NAMPTL3MBTL1MAPTTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |