Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301886 | 0.95 | KDM4E (0.57) | KDM4EAKR1C3ALDH1A1LMNAHTT | |
| SCHEMBL7309058 | 0.90 | AKR1C3 (0.56) | KDM4EAKR1C3LMNAHTTMEN1 | |
| SCHEMBL7306282 | 0.87 | AKR1C3 (0.52) | KDM4EAKR1C3LMNAHTTMEN1 | |
| SCHEMBL6852416 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL2677776 | 0.83 | CNR2 (0.62) | KDM4ELMNAHTTMEN1HTR1E | |
| SCHEMBL830749 | 0.83 | RAB9A (0.64) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL7310126 | 0.82 | CYP1A2 (0.52) | KDM4EAKR1C3ALDH1A1LMNAHTT | |
| SCHEMBL2677586 | 0.82 | CNR2 (0.63) | KDM4ELMNAHTTMEN1HTR1E | |
| SCHEMBL9188898 | 0.81 | FAAH (0.62) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7310135 | 0.81 | LMNA (0.62) | KDM4EAKR1C3ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |