Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311068 | 0.88 | KCNH2 (0.32) | ITGB3ITGA2BKMT2AMEN1KDM4E | |
| SCHEMBL7314699 | 0.86 | KCNH2 (0.32) | ITGB3ITGA2BKMT2AMEN1KDM4E | |
| SCHEMBL7309169 | 0.86 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7314252 | 0.86 | KCNH2 (0.30) | — | |
| SCHEMBL7310562 | 0.86 | ITGB3 (0.37) | GAAITGB3ITGA2BHTR2BKMT2A | |
| SCHEMBL7311904 | 0.85 | ITGB3 (0.32) | ITGB3ITGA2BKMT2AMEN1 | |
| SCHEMBL7313324 | 0.85 | ITGB3 (0.32) | ITGB3ITGA2B | |
| SCHEMBL7307030 | 0.82 | HTR2B (0.38) | ITGB3ITGA2BHTR2BKMT2AMEN1 | |
| SCHEMBL7313518 | 0.82 | HTR2B (0.38) | ITGB3ITGA2BHTR2BKMT2AMEN1 | |
| SCHEMBL7303264 | 0.81 | HTR2B (0.38) | ITGB3ITGA2BHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |