Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314926 | 0.92 | HTR2B (0.40) | HTR2BITGB3ITGA2BUSP30DRD2 | |
| SCHEMBL7311231 | 0.91 | HTR2B (0.36) | HTR2BITGB3ITGA2BUSP30 | |
| SCHEMBL7316515 | 0.90 | HTR2B (0.35) | HTR2BDRD2 | |
| SCHEMBL7309068 | 0.87 | HTR2B (0.41) | HTR2BITGB3ITGA2BUSP30TP53 | |
| SCHEMBL7310819 | 0.87 | HTR2B (0.39) | HTR2BUSP30DRD2 | |
| SCHEMBL7316825 | 0.85 | ITGB3 (0.34) | ITGB3ITGA2BDRD2 | |
| SCHEMBL7311107 | 0.85 | HTR2B (0.38) | HTR2BITGB3ITGA2B | |
| SCHEMBL7315937 | 0.84 | ITGB3 (0.35) | ITGB3ITGA2B | |
| SCHEMBL7238238 | 0.84 | VNN1 (0.35) | USP30TP53 | |
| SCHEMBL7306733 | 0.84 | GPR119 (0.33) | ITGB3ITGA2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |