Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297577 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL7305074 | 0.77 | HPGD (0.46) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL7307327 | 0.73 | HPGD (0.43) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL7307346 | 0.73 | TSHR (0.37) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL7305084 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL8577971 | 0.69 | HPGD (0.42) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL10353946 | 0.67 | HTT (0.50) | ALDH1A1HSD17B3HTTLMNAKMT2A | |
| SCHEMBL28710582 | 0.67 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL28429668 | 0.66 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL7308298 | 0.65 | HSP90AB1 (0.37) | ALDH1A1HPGDHSD17B10ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |