Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | FASN | P49327 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TCF4 | P15884 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63797 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL7305074 | 0.80 | HPGD (0.46) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL7308290 | 0.79 | HSP90AB1 (0.52) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL28710582 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL4388031 | 0.77 | MEN1 (0.55) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL29639745 | 0.77 | MEN1 (0.55) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL2943808 | 0.76 | HPGD (0.50) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL8577971 | 0.76 | HPGD (0.42) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL9752636 | 0.75 | FASN (0.61) | ALDH1A1HPGDALOX15TSHRRECQL | |
| SCHEMBL7044950 | 0.74 | HPGD (0.49) | ALDH1A1HPGDALOX15TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |