Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305074 | 0.76 | HPGD (0.46) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL7305084 | 0.76 | ALDH1A1 (0.50) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL28710582 | 0.69 | ALDH1A1 (0.59) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL7303631 | 0.69 | ALDH1A1 (0.40) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL7297577 | 0.68 | ALDH1A1 (0.39) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL28429668 | 0.68 | ALDH1A1 (0.42) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL28834964 | 0.67 | FASN (0.39) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL7299737 | 0.67 | TSHR (0.38) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL7307346 | 0.66 | TSHR (0.37) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL28494378 | 0.64 | ALDH1A1 (0.42) | HPGDALDH1A1TSHRALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |