Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7303629 | 0.98 | KIF11 (0.49) | KIF11MEN1KMT2ALTA4HTLR2 | |
| SCHEMBL7304875 | 0.93 | KIF11 (0.47) | KIF11KMT2ALTA4HTLR2CYP2C19 | |
| Hydrochloric Acid SCHEMBL7304869 | 0.92 | KIF11 (0.46) | KIF11KMT2ALTA4HTLR2CYP2C19 | |
| SCHEMBL7317999 | 0.87 | METAP2 (0.47) | KIF11MEN1KMT2ATLR2CYP2C19 | |
| SCHEMBL1839764 | 0.86 | METAP2 (0.52) | KIF11LTA4HCYP2C19METAP2MAPT | |
| SCHEMBL2553802 | 0.86 | METAP2 (0.52) | KIF11LTA4HCYP2C19METAP2MAPT | |
| SCHEMBL4141148 | 0.86 | METAP2 (0.52) | KIF11LTA4HCYP2C19METAP2MAPT | |
| Hydrochloric Acid SCHEMBL7317995 | 0.85 | METAP2 (0.46) | KIF11MEN1KMT2ATLR2CYP2C19 | |
| Hydrochloric Acid SCHEMBL3119114 | 0.85 | METAP2 (0.51) | KIF11LTA4HMETAP2MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4141147 | 0.85 | METAP2 (0.51) | KIF11LTA4HMETAP2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |