Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 5/20 | 0.32 |
| ▸ | HRH1 | P35367 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315964 | 0.95 | ITGB3 (0.40) | ITGB3ITGA2BHTR2BCYP2D6 | |
| SCHEMBL7315163 | 0.90 | ITGB3 (0.38) | ITGB3ITGA2BHTR2BCYP2D6GAA | |
| SCHEMBL7306996 | 0.90 | ITGB3 (0.38) | ITGB3ITGA2BHTR2BCYP2D6GAA | |
| SCHEMBL7309903 | 0.90 | ITGB3 (0.38) | ITGB3ITGA2BHTR2BCYP2D6MAPK1 | |
| SCHEMBL7307328 | 0.90 | ITGB3 (0.37) | ITGB3ITGA2BHTR2BCYP2D6 | |
| SCHEMBL7313170 | 0.89 | ITGB3 (0.38) | ITGB3ITGA2BHTR2BCYP2D6MAPK1 | |
| SCHEMBL7303852 | 0.88 | ITGB3 (0.38) | ITGB3ITGA2BHTR2BCYP2D6 | |
| SCHEMBL7311057 | 0.87 | ITGB3 (0.40) | ITGB3ITGA2BHTR2BCYP2D6GAA | |
| SCHEMBL7308042 | 0.86 | ITGB3 (0.34) | ITGB3ITGA2BHTR2B | |
| SCHEMBL7313564 | 0.85 | ITGB3 (0.39) | ITGB3ITGA2BHTR2BCYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |