Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.30 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 3/20 | 0.30 |
| ▸ | PLG | P00747 | 3/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.30 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306996 | 0.95 | ITGB3 (0.38) | ITGB3ITGA2BLMNAHTR2BKCNH2 | |
| SCHEMBL7307328 | 0.94 | ITGB3 (0.37) | ITGB3ITGA2BLMNAHTR2BKCNH2 | |
| SCHEMBL7311057 | 0.93 | ITGB3 (0.40) | ITGB3ITGA2BLMNAHTR2BKCNH2 | |
| SCHEMBL7315964 | 0.90 | ITGB3 (0.40) | ITGB3ITGA2BHTR2BCYP2D6 | |
| SCHEMBL7304200 | 0.89 | ITGB3 (0.36) | ITGB3ITGA2BLMNAHTR2BCYP2D6 | |
| SCHEMBL7303634 | 0.88 | ITGB3 (0.39) | ITGB3ITGA2BHTR2BCYP2D6 | |
| SCHEMBL7315730 | 0.87 | ITGB3 (0.33) | ITGB3ITGA2BLMNAHTR2B | |
| SCHEMBL7304230 | 0.85 | HTR2B (0.43) | ITGB3ITGA2BLMNAHTR2BCYP2D6 | |
| SCHEMBL7307194 | 0.84 | ACHE (0.42) | LMNAHTR2BF10PRSS1PRSS2 | |
| SCHEMBL8858166 | 0.83 | ITGB3 (0.33) | ITGB3ITGA2BHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |