SCHEMBL7303635

SCHEMBL7303635

O=C(CCCC1=Cc2ccccc2C1)C1CCN[C@H]1C(=O)N1CCSC1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 10/20 0.39
FAP Q12884 1/20 0.39
PREP P48147 7/20 0.38
DPP8 Q6V1X1 2/20 0.36
DPP9 Q86TI2 2/20 0.36
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7437380 0.88 DPP4 (0.33) DPP4FAPPREPDPP8DPP9
SCHEMBL7303628 0.84 DPP4 (0.38) DPP4FAPPREPDPP8DPP9
SCHEMBL7300891 0.81 PREP (0.48) DPP4FAPPREPDPP8DPP9
SCHEMBL7305077 0.78 PREP (0.53) DPP4FAPPREPDPP8DPP9
SCHEMBL7302071 0.76 PREP (0.62) PREP
SCHEMBL7302073 0.76 PREP (0.62) PREP
SCHEMBL7295946 0.76 PREP (0.60) DPP4FAPPREPDPP8DPP9
SCHEMBL8154287 0.76 PREP (0.60) DPP4FAPPREPDPP8DPP9
SCHEMBL8155765 0.76 PREP (0.60) DPP4FAPPREPDPP8DPP9
SCHEMBL9048453 0.74 PREP (0.37) DPP4FAPPREPACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed