SCHEMBL730366

SCHEMBL730366

CCCCOC(=O)CC(C(=O)OCCCC)N(CCC)[Si](OCC)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 1/20 0.36
NAAA Q02083 1/20 0.35
ALDH1A1 P00352 1/20 0.34
DNM1 Q05193 1/20 0.33
ATM Q13315 1/20 0.33
TSHR P16473 2/20 0.32
DGKA P23743 1/20 0.32
RAD52 P43351 1/20 0.31
HPGD P15428 1/20 0.31
GAA P10253 1/20 0.31
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729847 0.94 MAPK1 (0.34) MAPK1NPSR1L3MBTL1MAPTNAAA
SCHEMBL728382 0.88 NPSR1 (0.36) MAPK1NPSR1L3MBTL1MAPTNAAA
SCHEMBL728459 0.86 ALDH1A1 (0.34) ALDH1A1TSHRGAA
SCHEMBL730159 0.80 ALDH1A1 (0.35) ALDH1A1TSHRGAA
SCHEMBL730206 0.74 ALDH1A1 (0.37) ALDH1A1TSHRGAA
SCHEMBL728621 0.74
SCHEMBL28565358 0.68 NAAA (0.53) MAPK1NPSR1L3MBTL1MAPTNAAA
SCHEMBL9539768 0.67 ALDH1A1 (0.50) MAPK1NPSR1L3MBTL1MAPTNAAA
SCHEMBL10477474 0.67 ALDH1A1 (0.50) MAPK1NPSR1L3MBTL1MAPTNAAA
SCHEMBL11114076 0.67 ALDH1A1 (0.50) MAPK1NPSR1L3MBTL1MAPTNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
EP-2393861-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY Momentive Performance Materials Inc. (US) 2011-12-14 EP disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed
WO-2010091338-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 WO disclosed