SCHEMBL728382

SCHEMBL728382

CCCCOC(=O)CC(C(=O)OCCCC)N(CCC)[Si](OC)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.36
MAPK1 P28482 2/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NAAA Q02083 1/20 0.36
ALDH1A1 P00352 1/20 0.35
DNM1 Q05193 1/20 0.34
ATM Q13315 1/20 0.33
DGKA P23743 1/20 0.33
RAD52 P43351 1/20 0.32
TSHR P16473 2/20 0.32
HPGD P15428 1/20 0.32
FAAH O00519 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729847 0.92 MAPK1 (0.34) NPSR1MAPK1MAPTL3MBTL1NAAA
SCHEMBL730366 0.88 MAPK1 (0.36) NPSR1MAPK1MAPTL3MBTL1NAAA
SCHEMBL730206 0.84 ALDH1A1 (0.37) ALDH1A1TSHRSMN1; SMN2
SCHEMBL728024 0.80 ZDHHC7 (0.33)
SCHEMBL730159 0.78 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL728025 0.75 LMNA (0.30)
SCHEMBL728459 0.72 ALDH1A1 (0.34) ALDH1A1TSHRSMN1; SMN2
SCHEMBL728621 0.72
SCHEMBL28565358 0.69 NAAA (0.53) NPSR1MAPK1MAPTL3MBTL1NAAA
SCHEMBL730336 0.69 USP2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
EP-2393861-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY Momentive Performance Materials Inc. (US) 2011-12-14 EP disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed
WO-2010091338-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 WO disclosed