Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.70 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.70 |
| ▸ | HTR3B | O95264 | 5/20 | 0.70 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.70 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302557 | 0.85 | HTR3E (0.70) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7302698 | 0.83 | HTR3A (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7302702 | 0.83 | HTR3A (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7439804 | 0.83 | HTR3E (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7438581 | 0.79 | HTR3E (0.85) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7300915 | 0.75 | HTR3E (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL8809153 | 0.75 | HTT (0.64) | KCNH2MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7435237 | 0.74 | HTR3A (0.78) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7309093 | 0.73 | KDM4E (0.65) | KCNH2EGLN1MEN1KMT2AKDM4E | |
| SCHEMBL8809110 | 0.72 | MEN1 (0.55) | KCNH2MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503844-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5155115-A | THIENOPYRIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0503844-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |