Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809110 | 0.88 | MEN1 (0.55) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8810033 | 0.84 | HTT (0.64) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8811244 | 0.83 | HTT (0.47) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7309093 | 0.76 | KDM4E (0.65) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7303669 | 0.75 | HTR3A (0.70) | MEN1KMT2ASMN1; SMN2KCNH2KDM4E | |
| SCHEMBL8807392 | 0.73 | MEN1 (0.55) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9410763 | 0.69 | KCNH2 (0.43) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10675617 | 0.69 | ALDH1A1 (0.58) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL22749178 | 0.69 | CNR2 (0.60) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13856994 | 0.69 | KMT2A (0.71) | HTTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505058-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1997-05-21 | — | — | EP | claimed |
| US-5219864-A | Prevention, treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | claimed |
| EP-0505058-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-23 | — | — | EP | claimed |
| EP-0505058-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5219864-A | Prevention, treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0505058-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |