Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075576 | 0.82 | — | — | |
| SCHEMBL14613262 | 0.72 | THRB (0.35) | — | |
| SCHEMBL104114 | 0.70 | — | — | |
| SCHEMBL611520 | 0.69 | — | — | |
| SCHEMBL3044996 | 0.68 | TDP1 (0.32) | TDP1 | |
| SCHEMBL7303672 | 0.67 | ALDH1A1 (0.31) | ALDH1A1TSHRTDP1 | |
| SCHEMBL28203 | 0.66 | — | — | |
| SCHEMBL13001679 | 0.66 | TDP1 (0.38) | TDP1 | |
| SCHEMBL498009 | 0.66 | — | — | |
| SCHEMBL20047841 | 0.66 | DGAT1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |