Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302754 | 0.95 | NPC1 (0.72) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7305315 | 0.90 | ALDH1A1 (0.59) | NPC1RAB9ATSHRLMNAHPGD | |
| SCHEMBL7312036 | 0.86 | DPP4 (0.60) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7218802 | 0.83 | HPGD (0.73) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL29941490 | 0.81 | HPGD (0.71) | NPC1RAB9ATSHRLMNAHPGD | |
| SCHEMBL10197843 | 0.81 | HPGD (0.71) | NPC1RAB9ATSHRLMNAHPGD | |
| SCHEMBL2614250 | 0.80 | TSHR (0.71) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL4310722 | 0.80 | TSHR (0.84) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL27297526 | 0.80 | NPC1 (0.70) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL10282916 | 0.79 | NPC1 (0.74) | NPC1RAB9ADRD4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |