Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312036 | 0.96 | DPP4 (0.60) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL7303743 | 0.90 | NPC1 (0.65) | MAPTDPP4DPP8NPC1RAB9A | |
| SCHEMBL16442058 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KDM4EGRM3L3MBTL1HPGD | |
| SCHEMBL1520334 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KDM4EGRM3L3MBTL1HPGD | |
| SCHEMBL7232912 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KDM4EGRM3L3MBTL1HPGD | |
| SCHEMBL7302754 | 0.83 | NPC1 (0.72) | MAPTNPC1RAB9ALMNATSHR | |
| SCHEMBL29941490 | 0.81 | HPGD (0.71) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL10197843 | 0.81 | HPGD (0.71) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL5031105 | 0.80 | HSD11B1 (0.55) | ALDH1A1MEN1KMT2AGRM3LMNA | |
| SCHEMBL7310175 | 0.80 | HPGD (0.64) | ALDH1A1MEN1KMT2AMAPTGRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |