Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452125 | 1.00 | ST14 (0.54) | ST14RAB9ANPC1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9269736 | 0.99 | ST14 (0.53) | ST14RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7299564 | 0.89 | MAPT (0.57) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7303302 | 0.88 | ITGB3 (0.66) | ST14RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL9272405 | 0.88 | ITGB3 (0.66) | ST14RAB9ANPC1MAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL9274585 | 0.86 | MAPT (0.57) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7303344 | 0.85 | ST14 (0.59) | ST14RAB9ANPC1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9272571 | 0.84 | ST14 (0.58) | ST14RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7283709 | 0.83 | ITGB3 (0.52) | ST14MAPTITGB3ITGA2BKMT2A | |
| SCHEMBL9272551 | 0.83 | RAB9A (0.61) | RAB9ANPC1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |
| JP-2235853-A | — | — | None | — | — | JP | disclosed |
| EP-0714295-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5399585-A | Anitcoagulants, antiinflammatory, antitumor | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | disclosed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5084466-A | Anticoagulants, antiinflammatory agents, atheriosclerosis and antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1992-01-28 | — | — | US | disclosed |
| JP-H02235853-A | CARBOXYLIC ESTER DERIVATIVE | F HOFFMANN LA ROCHE AG | 1990-09-18 | — | — | JP | disclosed |