Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404644 | 1.00 | FDPS (0.50) | FDPSALDH1A1SMN1; SMN2POLBNPC1 | |
| SCHEMBL10781072 | 1.00 | FDPS (0.50) | FDPSALDH1A1SMN1; SMN2POLBNPC1 | |
| SCHEMBL9641322 | 0.81 | FDPS (0.46) | FDPSALDH1A1SMN1; SMN2POLBNPC1 | |
| SCHEMBL85479 | 0.78 | FDPS (0.53) | FDPSALDH1A1SMN1; SMN2POLBNPC1 | |
| SCHEMBL7747370 | 0.77 | RAB9A (0.54) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL7747367 | 0.77 | RAB9A (0.54) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL4034014 | 0.76 | FDPS (0.52) | FDPSALDH1A1SMN1; SMN2POLBNPC1 | |
| SCHEMBL19306616 | 0.76 | FDPS (0.47) | FDPSALDH1A1SMN1; SMN2POLBNPC1 | |
| SCHEMBL25083172 | 0.75 | FDPS (0.50) | FDPSALDH1A1SMN1; SMN2POLBNPC1 | |
| SCHEMBL9641327 | 0.75 | FDPS (0.50) | FDPSALDH1A1SMN1; SMN2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356796-A2 | Aminomethyl peptides, production process and their use as medicaments | BAYER AG (DE) | 1990-03-07 | — | — | EP | claimed |
| US-4818748-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | claimed |
| EP-0236874-A2 | Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes | BAYER AG (DE) | 1987-09-16 | — | — | EP | claimed |
| US-20170327517-A1 | Boronic Acid Inhibitors of HIV Protease | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-11-16 | — | — | US | disclosed |
| EP-3212196-A1 | BORONIC ACID INHIBITORS OF HIV PROTEASE | Wisconsin Alumni Research Foundation (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9738664-B2 | Boronic acid inhibitors of HIV protease | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-08-22 | — | — | US | disclosed |
| WO-2016069955-A1 | BORONIC ACID INHIBITORS OF HIV PROTEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-05-06 | — | — | WO | disclosed |
| US-20160122366-A1 | BORONIC ACID INHIBITORS OF HIV PROTEASE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-05-05 | — | — | US | disclosed |
| EP-0564972-B1 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AG (DE) | 1999-08-11 | — | — | EP | disclosed |
| EP-0455133-B1 | Peptide antagonists of bradykinin | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0413277-B1 | Peptide antagonists of bradykinin | HOECHST AG (DE) | 1994-11-23 | — | — | EP | disclosed |
| EP-0144230-B1 | GROWTH PROMOTANTS FOR ANIMALS | Pfizer Limited (GB) | 1990-08-08 | — | — | EP | disclosed |
| EP-0356796-A2 | Aminomethyl peptides, production process and their use as medicaments | BAYER AG (DE) | 1990-03-07 | — | — | EP | disclosed |
| US-4818748-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0236874-A2 | Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes | BAYER AG (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4562197-A | CATTLE, POULTRY | PFIZER INC. (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0144230-A2 | Growth promotants for animals | Pfizer Limited (GB) | 1985-06-12 | — | — | EP | disclosed |
| US-4504414-A | Synthetic pyridyl-alanyl decapeptides having antiovulatory activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1985-03-12 | — | — | US | disclosed |
| US-4504414-A | Synthetic pyridyl-alanyl decapeptides having antiovulatory activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1985-03-12 | — | — | US | disclosed |
| US-4504414-A | Synthetic pyridyl-alanyl decapeptides having antiovulatory activity | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1985-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122366-A1 | BORONIC ACID INHIBITORS OF HIV PROTEASE | PREP, DNPEP, PEPD | FDPS 1516/4885ALDH1A1 2837/4885SMN1; SMN2 3374/4885 |
| US-20170327517-A1 | Boronic Acid Inhibitors of HIV Protease | PREP, DNPEP, PEPD | FDPS 1516/4885ALDH1A1 2837/4885SMN1; SMN2 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.