Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303922 | 0.88 | NR4A3 (0.42) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL1290821 | 0.85 | NR4A3 (0.42) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL7304782 | 0.78 | KDM4E (0.50) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL23728541 | 0.76 | HSD11B1 (0.53) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL23938203 | 0.76 | CYP17A1 (0.33) | KDM4ETLR8ALDH1A1HPGDRAB9A | |
| SCHEMBL20731191 | 0.75 | TLR8 (0.33) | TLR8 | |
| SCHEMBL9279114 | 0.74 | KDM4E (0.44) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL25367626 | 0.73 | KDM4E (0.39) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL7307084 | 0.71 | RAB9A (0.52) | KDM4EALDH1A1HPGDRAB9AHIF1A | |
| SCHEMBL1290672 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1HPGDRAB9AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483836-A1 | Pyrazolo [1,5-a] pyridine-3-carboxylic acid derivatives, their preparation process and their use | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-05-06 | — | — | EP | claimed |
| US-5200415-A | Serotonin receptor antagonists; antiemetics, antianxietics | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0483836-A1 | Pyrazolo [1,5-a] pyridine-3-carboxylic acid derivatives, their preparation process and their use | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-05-06 | — | — | EP | disclosed |