Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303862 | 0.88 | NR4A3 (0.48) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL7307084 | 0.83 | RAB9A (0.52) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL1290821 | 0.83 | NR4A3 (0.42) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL7302190 | 0.77 | GABRP (0.37) | NR4A3PPARGKDM4E | |
| SCHEMBL7304782 | 0.76 | KDM4E (0.50) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL7302714 | 0.72 | CHRNA7 (0.46) | ALDH1A1GAA | |
| SCHEMBL7300575 | 0.72 | HTR3A (0.52) | — | |
| SCHEMBL9279114 | 0.72 | KDM4E (0.44) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL25367626 | 0.71 | KDM4E (0.39) | NR4A3KDM4ETLR8ALDH1A1TDP1 | |
| SCHEMBL1290672 | 0.69 | KDM4E (0.41) | PPARGKDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200415-A | Serotonin receptor antagonists; antiemetics, antianxietics | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0483836-A1 | Pyrazolo [1,5-a] pyridine-3-carboxylic acid derivatives, their preparation process and their use | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-05-06 | — | — | EP | disclosed |