Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141390 | 0.71 | CA2 (0.31) | CA2 | |
| SCHEMBL979771 | 0.70 | — | — | |
| SCHEMBL7343487 | 0.64 | CA1 (0.36) | CA1CA9 | |
| SCHEMBL981029 | 0.64 | CALM1 (0.42) | CA1CA9 | |
| SCHEMBL30103465 | 0.63 | CA2 (0.31) | CA2 | |
| SCHEMBL8771756 | 0.63 | — | — | |
| SCHEMBL7303716 | 0.62 | HIF1A (0.43) | CA1CA9HIF1AEPAS1ALOX5 | |
| SCHEMBL29077124 | 0.58 | — | — | |
| SCHEMBL10943194 | 0.57 | CA2 (0.33) | CA2 | |
| SCHEMBL2901854 | 0.57 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372940-A2 | Anti-inflammatory 2-furanones | ALLERGAN, INC (US) | 1990-06-13 | — | — | EP | disclosed |