Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2714458 | 0.85 | ALDH1A1 (0.50) | LMNAMAPK1HTTRAB9ACYP3A4 | |
| SCHEMBL336060 | 0.84 | KDM4E (0.52) | CES2CES1LMNAMAPK1HTT | |
| SCHEMBL4358318 | 0.82 | TDP1 (0.55) | CES2CES1SIRT5CYP3A4KDM4E | |
| SCHEMBL27350624 | 0.82 | HSD17B10 (0.57) | LMNARAB9AKDM4EHSD17B10CDC25A | |
| SCHEMBL1401558 | 0.81 | CA12 (0.54) | LMNAMAPK1HTTRAB9ACYP3A4 | |
| SCHEMBL17478757 | 0.78 | AKR1C3 (0.53) | — | |
| SCHEMBL2581290 | 0.78 | PARP1 (0.47) | CES2CES1SIRT5CYP3A4KDM4E | |
| SCHEMBL29436298 | 0.77 | KDM4E (0.50) | LMNAHTTRAB9AKDM4EHSD17B10 | |
| SCHEMBL14421297 | 0.76 | POLB (0.53) | CES2CES1LMNAMAPK1HTT | |
| SCHEMBL17262460 | 0.76 | SORT1 (0.45) | CES2CES1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138257-B1 | Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-03-20 | — | — | US | disclosed |
| US-6639042-B1 | Organic solvent soluble | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-10-28 | — | — | US | disclosed |
| US-6512124-B1 | N-(3,5-bis(4-hydroxybenzoyl)benzene)-4-fluoroisophthalimide. Aromatic polyimides (Pls) are well known, high-performance materials with widespread applications in the aerospace and electronics industries due to their excellent thermomechanical | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-01-28 | — | — | US | disclosed |