SCHEMBL4358318

SCHEMBL4358318

O=C(c1ccc(F)c(C(=O)O)c1)c1ccc(F)c(C(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
POLB P06746 1/20 0.55
CDC25A P30304 1/20 0.52
CDC25B P30305 1/20 0.52
HSD17B10 Q99714 1/20 0.52
SRD5A2 P31213 5/20 0.46
KDM4E B2RXH2 2/20 0.46
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
HSD17B14 Q9BPX1 1/20 0.44
SIRT5 Q9NXA8 1/20 0.43
CYP3A4 P08684 1/20 0.42
ASPH Q12797 1/20 0.42
KDM8 Q8N371 1/20 0.42
DHODH Q02127 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ATM Q13315 1/20 0.41
NR4A1 P22736 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14421297 0.92 POLB (0.53) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL3652414 0.89 AKR1C3 (0.54) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL336060 0.89 KDM4E (0.52) L3MBTL1POLBCDC25ACDC25BHSD17B10
SCHEMBL17478757 0.83 AKR1C3 (0.53)
SCHEMBL2581290 0.83 PARP1 (0.47) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL31052933 0.82 TDP1 (0.57) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL730390 0.82 CES2 (0.41) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL17262460 0.80 SORT1 (0.45) CDC25ACDC25BHSD17B10KDM4ECES2
SCHEMBL48886 0.79 POLB (0.80) TDP1L3MBTL1POLBCDC25ACDC25B
SCHEMBL29404709 0.79 POLB (0.80) TDP1L3MBTL1POLBCDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288058-B2 Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode MITSUI CHEMICALS, INC. (JP) 2012-10-16 US disclosed
EP-1788649-B1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE MITSUI CHEMICALS INC (JP) 2012-09-26 EP disclosed
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 US disclosed
EP-1612232-B1 CROSSLINKED IONICALLY CONDUCTING RESIN, AND IONICALLY CONDUCTING POLYMER MEMBRANES, BINDERS AND FUEL CELLS, MADE BY USING THE RESIN MITSUI CHEMICALS INC (JP) 2007-09-19 EP disclosed
EP-1788649-A1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE Mitsui Chemicals, Inc. (JP) 2007-05-23 EP disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed