Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305027 | 0.80 | NPC1 (0.30) | — | |
| SCHEMBL7306938 | 0.75 | BACE1 (0.39) | BACE1BACE2ULK1 | |
| SCHEMBL7307325 | 0.70 | LIMK1 (0.33) | — | |
| SCHEMBL7306926 | 0.63 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL5880375 | 0.61 | WNT3A (0.34) | — | |
| SCHEMBL7299546 | 0.61 | WNT3A (0.34) | — | |
| SCHEMBL19477810 | 0.61 | MAPK10 (0.53) | BACE1 | |
| SCHEMBL29463913 | 0.61 | MAPK10 (0.53) | BACE1 | |
| Hydrochloric Acid SCHEMBL5880349 | 0.60 | WNT3A (0.34) | — | |
| SCHEMBL18095874 | 0.59 | LIMK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556008-B1 | Condensed imidazopyridine derivatives with psychotropic activity | SHIONOGI & CO (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5461062-A | Psychotropic agent as antianxiety agent, anesthesia antagonistic agent | SHIONOGI & CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5378848-A | Benzodiazepine agonist, psychotropic, antianxiety, cerebral function activator, anesthesia atagonist | SHIONOGI & CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0556008-A1 | Condensed imidazopyridine derivatives with psychotropic activity | SHIONOGI & CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |