Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304154 | 0.75 | BACE1 (0.35) | BACE1BACE2ULK1 | |
| SCHEMBL7306926 | 0.71 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL29463913 | 0.61 | MAPK10 (0.53) | BACE1ALDH1A1 | |
| SCHEMBL19477810 | 0.61 | MAPK10 (0.53) | BACE1ALDH1A1 | |
| SCHEMBL7305027 | 0.59 | NPC1 (0.30) | — | |
| SCHEMBL17032461 | 0.56 | EPHX2 (0.37) | BACE1BACE2ALDH1A1 | |
| SCHEMBL23794886 | 0.55 | MAPT (0.62) | ALDH1A1 | |
| SCHEMBL23794890 | 0.55 | GAA (0.46) | ALDH1A1 | |
| SCHEMBL10187117 | 0.54 | — | — | |
| SCHEMBL84838 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556008-B1 | Condensed imidazopyridine derivatives with psychotropic activity | SHIONOGI & CO (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5461062-A | Psychotropic agent as antianxiety agent, anesthesia antagonistic agent | SHIONOGI & CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5378848-A | Benzodiazepine agonist, psychotropic, antianxiety, cerebral function activator, anesthesia atagonist | SHIONOGI & CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0556008-A1 | Condensed imidazopyridine derivatives with psychotropic activity | SHIONOGI & CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |