Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 3/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295408 | 0.72 | ACHE (0.52) | — | |
| SCHEMBL18095874 | 0.72 | LIMK1 (0.47) | LIMK1WNT3ATNKS2 | |
| SCHEMBL7304154 | 0.70 | BACE1 (0.35) | — | |
| SCHEMBL9583264 | 0.67 | ACHE (0.67) | — | |
| SCHEMBL30695898 | 0.67 | LIMK1 (0.30) | LIMK1 | |
| SCHEMBL1210409 | 0.67 | LIMK1 (0.30) | LIMK1 | |
| SCHEMBL30022769 | 0.64 | LIMK1 (0.34) | LIMK1WNT3ATNKS2 | |
| SCHEMBL16447529 | 0.64 | WNT3A (0.37) | LIMK1WNT3ATNKS2 | |
| SCHEMBL4825728 | 0.63 | LIMK1 (0.35) | LIMK1 | |
| SCHEMBL23009509 | 0.63 | HSP90AA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556008-B1 | Condensed imidazopyridine derivatives with psychotropic activity | SHIONOGI & CO (JP) | 1997-05-14 | — | — | EP | disclosed |
| US-5461062-A | Psychotropic agent as antianxiety agent, anesthesia antagonistic agent | SHIONOGI & CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5378848-A | Benzodiazepine agonist, psychotropic, antianxiety, cerebral function activator, anesthesia atagonist | SHIONOGI & CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0556008-A1 | Condensed imidazopyridine derivatives with psychotropic activity | SHIONOGI & CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |