Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HSD17B3 | P37058 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 2/20 | 0.40 |
| ▸ | TCF4 | P15884 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304300 | 0.83 | HPGD (0.52) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL28488463 | 0.83 | HSD17B10 (0.57) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL8577020 | 0.82 | HPGD (0.50) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL20207163 | 0.81 | HSD17B3 (0.55) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL6727835 | 0.79 | HSD17B3 (0.53) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL10599990 | 0.79 | HSD17B3 (0.53) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL10600090 | 0.79 | HSD17B3 (0.53) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL11620046 | 0.78 | HMGB1 (0.53) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL9417188 | 0.78 | ESR1 (0.53) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL946114 | 0.78 | ALDH1A1 (0.66) | HPGDALDH1A1ALOX15TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |