Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304310 | 0.83 | HPGD (0.57) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL8577020 | 0.82 | HPGD (0.50) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL10497530 | 0.77 | HSD17B3 (0.55) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL12232545 | 0.77 | HSD17B3 (0.55) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL7298746 | 0.75 | HSD17B3 (0.48) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL5570090 | 0.74 | HSD17B3 (0.52) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL7303953 | 0.73 | HPGD (0.42) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL16803280 | 0.72 | HSD17B3 (0.50) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL5565349 | 0.72 | CES2 (0.50) | HPGDALDH1A1TSHRALOX15RECQL | |
| SCHEMBL20207163 | 0.72 | HSD17B3 (0.55) | HPGDALDH1A1TSHRALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |