Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314851 | 0.94 | TNF (0.41) | ITGB3ITGA2BALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7299651 | 0.85 | GRM5 (0.41) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL6474441 | 0.84 | POLB (0.52) | ITGB3ITGA2BALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7300441 | 0.80 | GRM5 (0.40) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2POLB | |
| SCHEMBL6474034 | 0.78 | POLB (0.50) | ITGB3ITGA2BALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6475204 | 0.77 | PKM (0.49) | ITGB3ITGA2BALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6481898 | 0.71 | PKM (0.48) | ITGB3ITGA2BALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL24080887 | 0.70 | TNF (0.39) | ITGB3ITGA2BALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL24080889 | 0.69 | KAT2B (0.38) | ITGB3ITGA2BALDH1A1KAT2BLMNA | |
| SCHEMBL12283353 | 0.65 | MCHR1 (0.49) | ITGB3ITGA2BALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | disclosed |