Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299651 | 0.95 | GRM5 (0.41) | GRM5GRM3TMEM97SIGMAR1SLC6A2 | |
| SCHEMBL7314851 | 0.86 | TNF (0.41) | MAPTGRM4TNFGAAALDH1A1 | |
| SCHEMBL6481898 | 0.85 | PKM (0.48) | MAPTTMEM97SIGMAR1SLC6A2HRH2 | |
| SCHEMBL6475204 | 0.80 | PKM (0.49) | TMEM97SIGMAR1SLC6A2HRH2HRH1 | |
| SCHEMBL7304398 | 0.80 | ITGB3 (0.38) | TNFPKMPOLBALDH1A1CYP1A2 | |
| SCHEMBL6474034 | 0.78 | POLB (0.50) | MAPTTNFPKMPOLBALDH1A1 | |
| SCHEMBL6480916 | 0.76 | ITGB3 (0.47) | SMN1; SMN2 | |
| SCHEMBL6474441 | 0.71 | POLB (0.52) | PKMPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6474409 | 0.71 | ITGB3 (0.46) | PKMSMN1; SMN2 | |
| SCHEMBL2526216 | 0.68 | ALDH1A1 (0.64) | PKMPOLBALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0854140-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | disclosed |