Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297503 | 0.92 | L3MBTL1 (0.36) | L3MBTL3L3MBTL1KDM4EALDH1A1BACE1 | |
| SCHEMBL7303605 | 0.89 | ITGB3 (0.45) | ITGB3ITGA2BALOX15L3MBTL3L3MBTL1 | |
| SCHEMBL7303596 | 0.89 | ITGB3 (0.45) | ITGB3ITGA2BALOX15L3MBTL3L3MBTL1 | |
| SCHEMBL7303591 | 0.89 | ITGB3 (0.45) | ITGB3ITGA2BALOX15L3MBTL3L3MBTL1 | |
| SCHEMBL7306124 | 0.86 | ITGB3 (0.39) | ITGB3ITGA2BALOX15OPRL1OPRM1 | |
| SCHEMBL7306131 | 0.86 | ITGB3 (0.39) | ITGB3ITGA2BALOX15OPRL1OPRM1 | |
| SCHEMBL7298324 | 0.84 | ALK (0.45) | KDM4EBACE1POLBTDP1ALK | |
| SCHEMBL7304509 | 0.84 | BACE1 (0.34) | KDM4EALDH1A1BACE1OPRL1OPRM1 | |
| SCHEMBL7304305 | 0.78 | ITGB3 (0.37) | ITGB3ITGA2BALOX15KDM4EALDH1A1 | |
| SCHEMBL7304309 | 0.78 | ITGB3 (0.37) | ITGB3ITGA2BALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |