Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306131 | 1.00 | ITGB3 (0.39) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7293154 | 0.91 | ALDH1A1 (0.34) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7296172 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7296178 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7296184 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7304500 | 0.86 | ITGB3 (0.38) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7337996 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7305692 | 0.83 | ALK (0.40) | HRH3GPR119ALK | |
| SCHEMBL7304309 | 0.81 | ITGB3 (0.37) | ITGB3ITGA2BALOX15F2HRH3 | |
| SCHEMBL7304305 | 0.81 | ITGB3 (0.37) | ITGB3ITGA2BALOX15F2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |