Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883842 | 1.00 | ALDH1A1 (0.37) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL8692002 | 1.00 | ALDH1A1 (0.37) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL15974698 | 0.78 | FFAR3 (0.35) | ALDH1A1TSHRTP53 | |
| SCHEMBL28427435 | 0.77 | ALDH1A1 (0.39) | ALDH1A1ACEMMECPA1ACE2 | |
| SCHEMBL7263270 | 0.77 | TP53 (0.36) | TSHRTP53MEN1HPGDKMT2A | |
| SCHEMBL6894525 | 0.77 | HTT (0.47) | ALDH1A1HTTCA2MAPK1 | |
| SCHEMBL7309246 | 0.77 | TP53 (0.36) | TSHRTP53MEN1HPGDKMT2A | |
| SCHEMBL4457494 | 0.77 | HTT (0.47) | ALDH1A1HTTCA2MAPK1 | |
| SCHEMBL8883435 | 0.73 | TP53 (0.33) | TSHRTP53 | |
| SCHEMBL4885843 | 0.71 | HTT (0.36) | ALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1170832-C | Substituted thiazol [3,2-alpha] azatropylidene derivatives | ������������ʽ���� | 2004-10-13 | — | — | CN | disclosed |
| CN-1262275-A | Substituted thiazol [3,2-alpha] azatropylidene derivatives | EISAI CO LTD (JP) | 2000-08-09 | — | — | CN | disclosed |
| CN-1053908-C | Substituted thiazolo [3, 2-alpha ] aza * derivatives | EISAI CO LTD (JP) | 2000-06-28 | — | — | CN | disclosed |
| US-5801274-A | N- mercaptoacyl(amino acid or peptide)! compounds and S-lipophilic aliphatic carbonyl derivatives thereof as antihypertensives | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-09-01 | — | — | US | disclosed |
| US-5591891-A | PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-01-07 | — | — | US | disclosed |
| CN-1134152-A | Substituted thiazolo [3, 2-alpha ] aza * derivatives | EISAI CO LTD (JP) | 1996-10-23 | — | — | CN | disclosed |
| WO-1994017036-A1 | S-LIPOPHILIC ALIPHATIC CARBONYL [N-MERCAPTOACYL-(AMINO ACID OR PEPTIDE)] COMPOUNDS AS ANTIHYPERTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-08-04 | — | — | WO | disclosed |
| EP-0595878-A1 | ACYLMERCAPTOALKANOYLDIPEPTIDES, METHODS OF PREPARATION AND THEIR THERAPEUTIC USE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993002099-A1 | ACYLMERCAPTOALKANOYLDIPEPTIDES, METHODS OF PREPARATION AND THEIR THERAPEUTIC USE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-02-04 | — | — | WO | disclosed |
| EP-0524553-A1 | Acylmercaptoalkanoyldipeptides, methods of preparation and their therapeutic use | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-01-27 | — | — | EP | disclosed |