Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.41 |
| ▸ | HTR3B | O95264 | 3/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288976 | 0.89 | HTR3A (0.44) | HTR3AMEN1KMT2AHTR3EHTR3B | |
| SCHEMBL7284925 | 0.80 | MEN1 (0.46) | HTR3AMEN1KMT2AHTR3EHTR3B | |
| SCHEMBL7288791 | 0.77 | — | — | |
| SCHEMBL9199760 | 0.73 | HTR3A (0.58) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL9533289 | 0.67 | HTR3A (0.55) | HTR3AMEN1KMT2AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL9533542 | 0.66 | HTR3A (0.54) | HTR3AMEN1KMT2AHTR3EHTR3B | |
| SCHEMBL7435030 | 0.66 | HTR3A (0.72) | HTR3AKMT2AHTR3EHTR3BHTR3D | |
| SCHEMBL15495317 | 0.65 | MEN1 (0.59) | HTR3AMEN1KMT2AHTR3EHTR3B | |
| SCHEMBL9429391 | 0.65 | HTR3A (0.57) | HTR3AMEN1KMT2AHTR3EHTR3B | |
| SCHEMBL7435024 | 0.65 | NPC1 (0.63) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560348-B1 | Thieno 3,2-b pyridine derivatives for the treatment of gastrointestinal disorders | MITSUBISHI CHEM CORP (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-5352685-A | Gastrointestinal disorders | MITSUBISHI KASEI CORPORATION (JP) | 1994-10-04 | — | — | US | disclosed |