Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302893 | 0.85 | PREP (0.37) | PREPDPP4MTNR1BALOX5ALDH1A1 | |
| SCHEMBL7304730 | 0.74 | PREP (0.53) | PREPDPP4ALDH1A1NPSR1 | |
| SCHEMBL7303377 | 0.72 | PREP (0.42) | PREP | |
| SCHEMBL9050039 | 0.71 | PREP (0.48) | PREPDPP4 | |
| SCHEMBL9050399 | 0.69 | PREP (0.46) | PREP | |
| SCHEMBL7297458 | 0.69 | PREP (0.72) | PREPALOX5ALDH1A1CYP3A4TSHR | |
| SCHEMBL7295370 | 0.69 | PREP (0.71) | PREPDPP4ALOX5ALDH1A1MAPK1 | |
| SCHEMBL7304152 | 0.68 | LMNA (0.34) | PREPALDH1A1CYP3A4TSHRPEPD | |
| SCHEMBL7293107 | 0.65 | PREP (0.43) | PREPDPP4ALDH1A1MAPK1 | |
| SCHEMBL7298194 | 0.64 | PREP (0.52) | PREPDPP4MTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |