Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293090 | 0.89 | EDNRA (0.37) | EDNRAEDNRB | |
| SCHEMBL7295229 | 0.88 | EDNRA (0.37) | EDNRAEDNRB | |
| SCHEMBL7331793 | 0.83 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL7388129 | 0.80 | EDNRA (0.46) | EDNRAEDNRB | |
| SCHEMBL7391386 | 0.80 | EDNRA (0.46) | EDNRAEDNRB | |
| SCHEMBL7302716 | 0.79 | MAPK14 (0.35) | — | |
| SCHEMBL7297143 | 0.79 | DHPS (0.42) | EDNRA | |
| SCHEMBL7387930 | 0.77 | EDNRA (0.38) | EDNRAEDNRB | |
| SCHEMBL7301959 | 0.77 | EDNRA (0.38) | EDNRAEDNRB | |
| SCHEMBL7304764 | 0.77 | EDNRA (0.59) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | claimed |
| EP-0526708-B1 | Sulfonamide, preparation and use thereof as medicine and intermediate | HOFFMANN LA ROCHE (CH) | 2000-10-18 | — | — | EP | disclosed |
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | disclosed |