Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 10/20 | 0.46 |
| ▸ | EDNRB | P24530 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391386 | 1.00 | EDNRA (0.46) | EDNRAEDNRBGAALMNAHTT | |
| SCHEMBL7331793 | 0.91 | EDNRA (0.49) | EDNRAEDNRBDHPS | |
| SCHEMBL7304228 | 0.89 | EDNRA (0.58) | EDNRAEDNRBGAALMNAHTT | |
| SCHEMBL7302671 | 0.88 | EDNRA (0.43) | EDNRAEDNRBGAALMNAHTT | |
| SCHEMBL7303288 | 0.87 | EDNRA (0.46) | EDNRAEDNRBGAALMNAHTT | |
| SCHEMBL7297143 | 0.83 | DHPS (0.42) | EDNRADHPS | |
| SCHEMBL7304769 | 0.80 | EDNRA (0.37) | EDNRAEDNRB | |
| SCHEMBL7329858 | 0.80 | EDNRA (0.62) | EDNRAEDNRBDHPS | |
| SCHEMBL7328142 | 0.79 | EDNRA (0.48) | EDNRAEDNRBDHPS | |
| SCHEMBL7328712 | 0.78 | EDNRA (0.48) | EDNRAEDNRBDHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | claimed |